Eric Dane's Shocking 'Grey's Anatomy' Departure and Character's Fate Explored

Eric Dane portrayed Mark Sloan on Grey's Anatomy for seven seasons before his character met a tragic end in a plane crash.

Eric Dane's Journey on Grey's Anatomy

Dane joined the show in its second season in 2006 as plastic surgeon Mark Sloan and remained until season 9.

In an interview released posthumously in February 2026, Dane expressed pride in his career and the experiences gained from his time on the show.

Reason for Eric Dane's Departure

In a podcast episode from 2024, Dane suggested he was let go from Grey's Anatomy due to budget concerns, not related to his past struggles with prescription drugs.

He noted that the show's creator, Shonda Rhimes, handled his exit supportively.

Eric Dane's Reflection on His Final Scenes

Dane praised the show's handling of his character's departure and shared positive sentiments about his colleagues and Rhimes.

Grey's Anatomy aided Dane's battle with substance abuse by providing structure and support, as he revealed in an interview.

Grey's Anatomy Community's Response to Eric Dane's Passing

Eric Dane passed away in February 2026 at 53 after battling ALS. The show's production company and cast members expressed their condolences.

Dane is survived by his two daughters. If you need help with substance abuse, reach out to SAMHSA National Helpline at 1-800-662-HELP (4357).